CBX2
chromobox homolog 2
Synonyms:
CDCA6, M33, SRXY5
Species:
Human CBX2 (84733), Mouse Cbx2 (12416), Rat Cbx2 (303730), sheep CBX2 (101111469), cow CBX2 (506628), dog CBX2 (483349), naked mole-rat Cbx2 (101713651), Zebrafish cbx2 (327291), chicken CBX2 (426248), domestic guinea pig Cbx2 (100727193)
UniProtKB ID:
Gene ID:
- Human(84733) Summary: This gene encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of this gene in mice results in male-to-female gonadal sex reversal. Mutations in this gene are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Mar 2010]
- Mouse(12416) chromobox 2
- Rat(303730) chromobox homolog 2
- sheep(101111469) chromobox homolog 2
- cow(506628) chromobox homolog 2
- dog(483349) chromobox homolog 2
- naked mole-rat(101713651) chromobox homolog 2
- Zebrafish(327291) chromobox homolog 2 (Drosophila Pc class)
- chicken(426248) chromobox homolog 2
- domestic guinea pig(100727193) chromobox homolog 2
- domestic cat(101085589) chromobox homolog 2
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