DISC1
disrupted in schizophrenia 1
Synonyms:
C1orf136, SCZD9
Species:
Human DISC1 (27185), Mouse Disc1 (244667), Rat Disc1 (307940), domestic guinea pig Disc1 (100727415), dog DISC1 (488970), Zebrafish disc1 (407621), sheep DISC1 (101114672), chicken DISC1 (100859633), cow DISC1 (613555), Domestic Rabbit DISC1 (100356059) ...More
UniProtKB ID:
Gene ID:
- Human(27185) Summary: This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
- Mouse(244667) disrupted in schizophrenia 1
- Rat(307940) disrupted in schizophrenia 1
- domestic guinea pig(100727415) disrupted in schizophrenia 1
- dog(488970) disrupted in schizophrenia 1
- Zebrafish(407621) disrupted in schizophrenia 1
- sheep(101114672) disrupted in schizophrenia 1
- chicken(100859633) disrupted in schizophrenia 1
- cow(613555) disrupted in schizophrenia 1
- Domestic Rabbit(100356059) disrupted in schizophrenia 1
- naked mole-rat(101709649) disrupted in schizophrenia 1
- Horse(100060246) disrupted in schizophrenia 1
- domestic cat(101089719) disrupted in schizophrenia 1
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