DOT1L
DOT1-like histone H3K79 methyltransferase
Synonyms:
DOT1, KMT4
Species:
Human DOT1L (84444), Mouse Dot1l (208266), Rat Dot1l (362831), chicken DOT1L (420078), naked mole-rat Dot1l (101712712), Zebrafish dot1l (559945), dog DOT1L (485073), domestic guinea pig Dot1l (100713595), Horse DOT1L (100068506), domestic cat DOT1L (101101194) ...More
UniProtKB ID:
Gene ID:
- Human(84444) Summary: The protein encoded by this gene is a histone methyltransferase that methylates lysine-79 of histone H3. It is inactive against free core histones, but shows significant histone methyltransferase activity against nucleosomes. [provided by RefSeq, Aug 2011]
- Mouse(208266) DOT1-like, histone H3 methyltransferase (S. cerevisiae)
- Rat(362831) DOT1-like histone H3K79 methyltransferase
- chicken(420078) DOT1-like, histone H3 methyltransferase (S. cerevisiae)
- naked mole-rat(101712712) DOT1-like histone H3K79 methyltransferase
- Zebrafish(559945) DOT1-like, histone H3 methyltransferase (S. cerevisiae)
- dog(485073) DOT1-like, histone H3 methyltransferase (S. cerevisiae)
- domestic guinea pig(100713595) DOT1-like histone H3K79 methyltransferase
- Horse(100068506) DOT1-like, histone H3 methyltransferase (S. cerevisiae)
- domestic cat(101101194) DOT1-like, histone H3 methyltransferase (S. cerevisiae)
- sheep(101121261) DOT1-like, histone H3 methyltransferase (S. cerevisiae)
- cow(510442) DOT1-like histone H3K79 methyltransferase
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-DOT1L antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Monoclonal Anti-DOT1L antibody produced in mouse, clone 6A6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Proteins
Product Number
Description
Species
PrEST Antigen DOT1L, Prestige Antibodies® Powered by Atlas Antibodies, buffered aqueous solution,
Species
human