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Merck

FGA

fibrinogen alpha chain

Synonyms:
Fib2
Species:
UniProtKB ID:
Gene ID:
  • Human(2243) Summary: The protein encoded by this gene is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in two isoforms which vary in the carboxy-terminus. [provided by RefSeq, Jul 2008]
  • Mouse(14161) fibrinogen alpha chain
  • Rat(361969) fibrinogen alpha chain
  • chicken(396307) fibrinogen alpha chain
  • Zebrafish(378986) fibrinogen alpha chain
  • cow(522039) fibrinogen alpha chain
  • Horse(100069763) fibrinogen alpha chain
  • domestic cat(101092934) fibrinogen alpha chain
  • dog(475473) fibrinogen alpha chain
  • naked mole-rat(101697611) fibrinogen alpha chain
  • domestic guinea pig(100720646) fibrinogen alpha chain
  • Domestic Rabbit(100353616) fibrinogen alpha chain
  • sheep(101102090) fibrinogen alpha chain

Custom & Knockdown Gene Products

ELISA

Product Number
Description
Species
Human D-Dimer ELISA Kit, for serum, plasma, cell culture supernatants and urine,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-FGA, IgG fraction of antiserum,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-Fibrinogen antibody produced in goat, whole antiserum,
Species Reactivity
human
Application
ELISA
quantitative precipitin assay
Monoclonal Anti-Fibrinogen antibody produced in mouse, clone FG-21, ascites fluid,
Species Reactivity
baboon, human
Application
ELISA
Monoclonal Anti-Fibrinogen antibody produced in mouse, clone 85D4, ascites fluid,
Species Reactivity
baboon, bovine, canine, goat, human, pig, rabbit, sheep
Application
ELISA
dot blot

western blot

Proteins

Product Number
Description
Species
Fibrinopeptide A human, ≥96% (HPLC),
Species
human
Fibrinogen from bovine plasma, Type I-S, 65-85% protein (≥75% of protein is clottable),
Species
cow
Fibrin from human plasma, insoluble powder,
Species
human
Fibrinogen from human plasma, 50-70% protein (≥80% of protein is clottable),
Species
human
Fibrinogen from human plasma, 35-65% protein (≥90% of protein is clottable).,
Species
human