FHIT
fragile histidine triad
Synonyms:
AP3Aase, FRA3B
Species:
Human FHIT (2272), Mouse Fhit (14198), Rat Fhit (60398), Thale Cress FHIT (835936), domestic cat FHIT (101082731), dog FHIT (100215999), chicken FHIT (416071), cow FHIT (692183), naked mole-rat Fhit (101720165), domestic guinea pig Fhit (100735806) ...More
UniProtKB ID:
Gene ID:
- Human(2272) Summary: This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]
- Mouse(14198) fragile histidine triad gene
- Rat(60398) fragile histidine triad
- Thale Cress(835936) fragile histidine triad protein
- domestic cat(101082731) fragile histidine triad
- dog(100215999) fragile histidine triad
- chicken(416071) fragile histidine triad
- cow(692183) fragile histidine triad gene
- naked mole-rat(101720165) fragile histidine triad
- domestic guinea pig(100735806) fragile histidine triad
- sheep(100307043) fragile histidine triad
- Zebrafish(393713) fragile histidine triad gene
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