GLCE
glucuronic acid epimerase
Synonyms:
HSEPI
Species:
Human GLCE (26035), Mouse Glce (93683), Rat Glce (363073), chicken GLCE (415566), Horse GLCE (100052581), cow GLCE (281195), domestic guinea pig Glce (100733856), dog GLCE (487622), sheep GLCE (101106592), naked mole-rat Glce (101703064)
UniProtKB ID:
Gene ID:
- Human(26035) Summary: Heparan sulfate (HS) is a negatively charged cell surface polysaccharide required for the biologic activities of circulating extracellular ligands. GLCE is responsible for epimerization of D-glucuronic acid (GlcA) to L-iduronic acid (IdoA) of HS, which endows the nascent polysaccharide chain with the ability to bind growth factors and cytokines (Ghiselli and Agrawal, 2005 [PubMed 15853773]
- Mouse(93683) glucuronyl C5-epimerase
- Rat(363073) glucuronic acid epimerase
- chicken(415566) glucuronic acid epimerase
- Horse(100052581) glucuronic acid epimerase
- cow(281195) glucuronic acid epimerase
- domestic guinea pig(100733856) glucuronic acid epimerase
- dog(487622) glucuronic acid epimerase
- sheep(101106592) glucuronic acid epimerase
- naked mole-rat(101703064) glucuronic acid epimerase
- domestic cat(101095983) glucuronic acid epimerase
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