IARS
isoleucyl-tRNA synthetase
Synonyms:
IARS1, ILERS, ILRS, IRS, PRO0785
Species:
Human IARS (3376), Mouse Iars (105148), Rat Iars (306804), dog IARS (484216), domestic guinea pig Iars (100723914), naked mole-rat Iars (101700176), Horse IARS (100054721), cow IARS (509885), sheep IARS (101109674), Domestic Rabbit IARS (100356680) ...More
UniProtKB ID:
Gene ID:
- Human(3376) Summary: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Alternatively spliced transcript variants have been found. [provided by RefSeq, Nov 2012]
- Mouse(105148) isoleucine-tRNA synthetase
- Rat(306804) isoleucyl-tRNA synthetase
- dog(484216) isoleucyl-tRNA synthetase
- domestic guinea pig(100723914) isoleucyl-tRNA synthetase
- naked mole-rat(101700176) isoleucyl-tRNA synthetase
- Horse(100054721) isoleucyl-tRNA synthetase
- cow(509885) isoleucyl-tRNA synthetase
- sheep(101109674) isoleucyl-tRNA synthetase
- Domestic Rabbit(100356680) isoleucyl-tRNA synthetase
- Zebrafish(334393) isoleucyl-tRNA synthetase
- chicken(415957) isoleucyl-tRNA synthetase
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