IGF2R
insulin-like growth factor 2 receptor
Synonyms:
CD222, CIMPR, M6P-R, MPR1, MPRI
Species:
Human IGF2R (3482), Mouse Igf2r (16004), Rat Igf2r (25151), Zebrafish igf2r (557061), dog IGF2R (484067), Horse IGF2R (100058539), chicken IGF2R (395817), domestic guinea pig Igf2r (100725901), Goat IGF2R (100860744), cow IGF2R (281849) ...More
UniProtKB ID:
Gene ID:
- Human(3482) Summary: This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele. [provided by RefSeq, Apr 2013]
- Mouse(16004) insulin-like growth factor 2 receptor
- Rat(25151) insulin-like growth factor 2 receptor
- Zebrafish(557061) insulin-like growth factor 2 receptor
- dog(484067) insulin-like growth factor 2 receptor
- Horse(100058539) insulin-like growth factor 2 receptor
- chicken(395817) insulin-like growth factor 2 receptor
- domestic guinea pig(100725901) insulin-like growth factor 2 receptor
- Goat(100860744) insulin-like growth factor 2 receptor
- cow(281849) insulin-like growth factor 2 receptor
- domestic cat(100500935) insulin-like growth factor 2 receptor
- naked mole-rat(101707470) insulin-like growth factor 2 receptor
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