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Merck

MARK4

MAP/microtubule affinity-regulating kinase 4

Synonyms:
MARK4L, MARK4S, MARKL1, MARKL1L, PAR-1D
Species:
Human MARK4 (57787), Mouse Mark4 (232944), Rat Mark4 (680407), domestic guinea pig Mark4 (100733296), dog MARK4 (484449), naked mole-rat Mark4 (101726420), Horse MARK4 (100070770), domestic cat MARK4 (101084500), cow MARK4 (525675), sheep MARK4 (101115819)
UniProtKB ID:
Q96L34, Q8NG37, Q96JG7, Q96SQ2, Q9BYD8
Gene ID:
  • Human(57787) Summary: This gene encodes a member of the microtubule affinity-regulating kinase family. These protein kinases phosphorylate microtubule-associated proteins and regulate the transition between stable and dynamic microtubules. The encoded protein is associated with the centrosome throughout mitosis and may be involved in cell cycle control. Expression of this gene is a potential marker for cancer, and the encoded protein may also play a role in Alzheimer's disease. Pseudogenes of this gene are located on both the short and long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
  • Mouse(232944) MAP/microtubule affinity-regulating kinase 4
  • Rat(680407) MAP/microtubule affinity-regulating kinase 4
  • domestic guinea pig(100733296) MAP/microtubule affinity-regulating kinase 4
  • dog(484449) MAP/microtubule affinity-regulating kinase 4
  • naked mole-rat(101726420) MAP/microtubule affinity-regulating kinase 4
  • Horse(100070770) MAP/microtubule affinity-regulating kinase 4
  • domestic cat(101084500) MAP/microtubule affinity-regulating kinase 4
  • cow(525675) MAP/microtubule affinity-regulating kinase 4
  • sheep(101115819) MAP/microtubule affinity-regulating kinase 4

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB1300394
Anti-MARK4 (N-term) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry

Proteins

Product Number
Description
Species
SRP5046
MARK4, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human