MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
Synonyms:
Species:
Human MFNG (4242), Mouse Mfng (17305), Rat Mfng (315119), domestic cat MFNG (101097256), cow MFNG (505267), sheep MFNG (101103554), chicken MFNG (418042), Zebrafish mfng (493633), dog MFNG (610303), naked mole-rat Mfng (101722987)
UniProtKB ID:
Gene ID:
- Human(4242) Summary: This gene is a member of the fringe gene family which also includes radical and lunatic fringe genes. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. [provided by RefSeq, Oct 2009]
- Mouse(17305) MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
- Rat(315119) MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
- domestic cat(101097256) MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
- cow(505267) MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
- sheep(101103554) MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
- chicken(418042) MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
- Zebrafish(493633) manic fringe homolog
- dog(610303) MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
- naked mole-rat(101722987) MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
- domestic guinea pig(100731745) MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
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