MVP
major vault protein
Synonyms:
LRP, VAULT1
Species:
Human MVP (9961), Mouse Mvp (78388), Rat Mvp (64681), domestic guinea pig Mvp (100726794), Zebrafish mvp (373081), chicken MVP (420049), dog MVP (479783), naked mole-rat Mvp (101716080), Horse MVP (100063984), cow MVP (516456) ...More
UniProtKB ID:
Gene ID:
- Human(9961) Summary: This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012]
- Mouse(78388) major vault protein
- Rat(64681) major vault protein
- domestic guinea pig(100726794) major vault protein
- Zebrafish(373081) major vault protein
- chicken(420049) major vault protein
- dog(479783) major vault protein
- naked mole-rat(101716080) major vault protein
- Horse(100063984) major vault protein
- cow(516456) major vault protein
- Domestic Rabbit(100340748) major vault protein
- sheep(101119435) major vault protein
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