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Merck

NAT1

N-acetyltransferase 1 (arylamine N-acetyltransferase)

Synonyms:
AAC1, MNAT, NAT-1, NATI
Species:
Human NAT1 (9), Mouse Nat1 (17960), Rat Nat1 (116631), fruit fly NAT1 (46020), fruit fly Nat1 (32934), domestic cat NAT1 (101095575), cow NAT1 (512603), sheep NAT1 (101120889)
UniProtKB ID:
P18440, A8K4E7, O15159, O15300, Q546N1, Q96TE9
Gene ID:
  • Human(9) Summary: This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human genome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabolize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
  • Mouse(17960) N-acetyl transferase 1
  • Rat(116631) N-acetyltransferase 1
  • fruit fly(46020) CG3845 gene product from transcript CG3845-RA
  • fruit fly(32934) CG12202 gene product from transcript CG12202-RA
  • domestic cat(101095575) N-acetyltransferase 1 (arylamine N-acetyltransferase)
  • cow(512603) N-acetyltransferase 1 (arylamine N-acetyltransferase)
  • sheep(101120889) N-acetyltransferase 1 (arylamine N-acetyltransferase)

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