PDE4A
phosphodiesterase 4A, cAMP-specific
Synonyms:
DPDE2, PDE4, PDE46
Species:
Human PDE4A (5141), Mouse Pde4a (18577), Rat Pde4a (25638), sheep PDE4A (101117505), Domestic Rabbit PDE4A (100009247), Zebrafish pde4a (572061), domestic cat PDE4A (751107), dog PDE4A (100683695), chicken PDE4A (769860), domestic guinea pig Pde4a (100135594) ...More
UniProtKB ID:
Gene ID:
- Human(5141) Summary: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
- Mouse(18577) phosphodiesterase 4A, cAMP specific
- Rat(25638) phosphodiesterase 4A, cAMP-specific
- sheep(101117505) phosphodiesterase 4A, cAMP-specific
- Domestic Rabbit(100009247) phosphodiesterase 4A, cAMP-specific
- Zebrafish(572061) phosphodiesterase 4A, cAMP-specific
- domestic cat(751107) phosphodiesterase 4A, cAMP-specific
- dog(100683695) phosphodiesterase 4A, cAMP-specific
- chicken(769860) phosphodiesterase 4A, cAMP-specific
- domestic guinea pig(100135594) phosphodiesterase 4A, cAMP-specific
- cow(512222) phosphodiesterase 4A, cAMP-specific
- naked mole-rat(101717168) phosphodiesterase 4A, cAMP-specific
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Small Molecule - Activator
Product Number
Description
Species
Small Molecule - Antagonist
Product Number
Description
Species
Small Molecule - Inhibitor
Proteins
Product Number
Description
Species
PDE4A1A Active human, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),
Species
human