PEPD
peptidase D
Synonyms:
PROLIDASE
Species:
Human PEPD (5184), Mouse Pepd (18624), Rat Pepd (292808), domestic guinea pig Pepd (100722147), cow PEPD (615158), sheep PEPD (101110862), Horse PEPD (100056540), dog PEPD (476493), domestic cat PEPD (101083129), naked mole-rat Pepd (101725598) ...More
UniProtKB ID:
Gene ID:
- Human(5184) Summary: This gene encodes a member of the peptidase family. The protein forms a homodimer that hydrolyzes dipeptides or tripeptides with C-terminal proline or hydroxyproline residues. The enzyme serves an important role in the recycling of proline, and may be rate limiting for the production of collagen. Mutations in this gene result in prolidase deficiency, which is characterized by the excretion of large amount of di- and tri-peptides containing proline. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]
- Mouse(18624) peptidase D
- Rat(292808) peptidase D
- domestic guinea pig(100722147) peptidase D
- cow(615158) peptidase D
- sheep(101110862) peptidase D
- Horse(100056540) peptidase D
- dog(476493) peptidase D
- domestic cat(101083129) peptidase D
- naked mole-rat(101725598) peptidase D
- Zebrafish(337498) peptidase D
- chicken(415776) peptidase D
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