PHF8
PHD finger protein 8
Synonyms:
JHDM1F, MRXSSD, ZNF422
Species:
Human PHF8 (23133), Mouse Phf8 (320595), Rat Phf8 (317425), Zebrafish phf8 (566534), domestic cat PHF8 (101092337), dog PHF8 (491897), Horse PHF8 (100060410), cow PHF8 (513959), Domestic Rabbit PHF8 (100344764), sheep PHF8 (101118668) ...More
UniProtKB ID:
Gene ID:
- Human(23133) Summary: The protein encoded by this gene is a histone lysine demethylase that preferentially acts on histones in the monomethyl or dimethyl states. The encoded protein requires Fe(2+) ion, 2-oxoglutarate, and oxygen for its catalytic activity. Defects in this gene are a cause of mental retardation syndromic X-linked Siderius type (MRXSSD). Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010]
- Mouse(320595) PHD finger protein 8
- Rat(317425) PHD finger protein 8
- Zebrafish(566534) PHD finger protein 8
- domestic cat(101092337) PHD finger protein 8
- dog(491897) PHD finger protein 8
- Horse(100060410) PHD finger protein 8
- cow(513959) PHD finger protein 8
- Domestic Rabbit(100344764) PHD finger protein 8
- sheep(101118668) PHD finger protein 8
- domestic guinea pig(100721757) PHD finger protein 8
- naked mole-rat(101716284) PHD finger protein 8
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