PMVK
phosphomevalonate kinase
Synonyms:
HUMPMKI, PMK, PMKA, PMKASE
Species:
Human PMVK (10654), Mouse Pmvk (68603), Rat Pmvk (310645), domestic guinea pig Pmvk (100733721), cow PMVK (513533), chicken PMVK (101666934), Zebrafish pmvk (100003383), domestic cat PMVK (101096787), dog PMVK (612251), sheep PMVK (101113026) ...More
UniProtKB ID:
Gene ID:
- Human(10654) Summary: This gene encodes a peroxisomal enzyme that catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate, the fifth reaction of the cholesterol biosynthetic pathway. Studies in rat show that the message level and the enzyme activity of this protein is regulated by sterol, and that this regulation is coordinated with 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate-limiting enzyme of cholesterol biosynthesis. [provided by RefSeq, Sep 2011]
- Mouse(68603) phosphomevalonate kinase
- Rat(310645) phosphomevalonate kinase
- domestic guinea pig(100733721) phosphomevalonate kinase
- cow(513533) phosphomevalonate kinase
- chicken(101666934) phosphomevalonate kinase
- Zebrafish(100003383) phosphomevalonate kinase
- domestic cat(101096787) phosphomevalonate kinase
- dog(612251) phosphomevalonate kinase
- sheep(101113026) phosphomevalonate kinase
- naked mole-rat(101720089) phosphomevalonate kinase
- chicken(101747962) phosphomevalonate kinase
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