PTS
6-pyruvoyltetrahydropterin synthase
Synonyms:
PTPS
Species:
Human PTS (5805), Mouse Pts (19286), Rat Pts (29498), fruit fly pts (252458), Zebrafish pts (100073330), chicken PTS (374144), dog PTS (611326), domestic cat PTS (101096347), cow PTS (506860), sheep PTS (101108950) ...More
UniProtKB ID:
Gene ID:
- Human(5805) Summary: The enzyme encoded by this gene catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH(4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia. [provided by RefSeq, Oct 2008]
- Mouse(19286) 6-pyruvoyl-tetrahydropterin synthase
- Rat(29498) 6-pyruvoyl-tetrahydropterin synthase
- fruit fly(252458) ponte thermosensible
- Zebrafish(100073330) 6-pyruvoyltetrahydropterin synthase
- chicken(374144) 6-pyruvoyltetrahydropterin synthase
- dog(611326) 6-pyruvoyltetrahydropterin synthase
- domestic cat(101096347) 6-pyruvoyltetrahydropterin synthase
- cow(506860) 6-pyruvoyltetrahydropterin synthase
- sheep(101108950) 6-pyruvoyltetrahydropterin synthase
- domestic guinea pig(100733894) 6-pyruvoyltetrahydropterin synthase
- naked mole-rat(101705212) 6-pyruvoyltetrahydropterin synthase
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