RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
Synonyms:
CNrasGEF, NRAPGEP, PDZ-GEF1, PDZGEF1, RA-GEF, Rap-GEP, nRap GEP
Species:
Human RAPGEF2 (9693), Mouse Rapgef2 (76089), Rat Rapgef2 (310533), domestic guinea pig Rapgef2 (100725060), naked mole-rat Rapgef2 (101718791), sheep RAPGEF2 (101111578), Domestic Rabbit RAPGEF2 (100346752), dog RAPGEF2 (482670), domestic cat RAPGEF2 (101084954), Horse RAPGEF2 (100069003) ...More
UniProtKB ID:
Gene ID:
- Human(9693) Summary: Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF2, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]
- Mouse(76089) Rap guanine nucleotide exchange factor (GEF) 2
- Rat(310533) Rap guanine nucleotide exchange factor (GEF) 2
- domestic guinea pig(100725060) Rap guanine nucleotide exchange factor (GEF) 2
- naked mole-rat(101718791) Rap guanine nucleotide exchange factor (GEF) 2
- sheep(101111578) Rap guanine nucleotide exchange factor (GEF) 2
- Domestic Rabbit(100346752) Rap guanine nucleotide exchange factor (GEF) 2
- dog(482670) Rap guanine nucleotide exchange factor (GEF) 2
- domestic cat(101084954) Rap guanine nucleotide exchange factor (GEF) 2
- Horse(100069003) Rap guanine nucleotide exchange factor (GEF) 2
- cow(100139484) Rap guanine nucleotide exchange factor (GEF) 2
- Zebrafish(557693) Rap guanine nucleotide exchange factor (GEF) 2
- chicken(422418) Rap guanine nucleotide exchange factor (GEF) 2
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-RAPGEF2 antibody produced in mouse, clone 1E8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-RAPGEF2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
Anti-RAPGEF2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Proteins
Product Number
Description
Species
PrEST Antigen RAPGEF2, Prestige Antibodies® Powered by Atlas Antibodies, buffered aqueous solution,
Species
human