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Merck

RNF40

ring finger protein 40, E3 ubiquitin protein ligase

Synonyms:
BRE1B, RBP95, STARING
Species:
UniProtKB ID:
Gene ID:
  • Human(9810) Summary: The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
  • Mouse(233900) ring finger protein 40
  • Rat(266712) ring finger protein 40, E3 ubiquitin protein ligase
  • Zebrafish(798088) ring finger protein 40
  • dog(489913) ring finger protein 40, E3 ubiquitin protein ligase
  • Horse(100065215) ring finger protein 40, E3 ubiquitin protein ligase
  • naked mole-rat(101701173) ring finger protein 40, E3 ubiquitin protein ligase
  • domestic guinea pig(100714613) ring finger protein 40, E3 ubiquitin protein ligase
  • sheep(101102446) ring finger protein 40, E3 ubiquitin protein ligase
  • domestic cat(101092073) ring finger protein 40, E3 ubiquitin protein ligase
  • cow(539901) ring finger protein 40, E3 ubiquitin protein ligase

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