SPEN
spen homolog, transcriptional regulator (Drosophila)
Synonyms:
HIAA0929, MINT, RBM15C, SHARP
Species:
Human SPEN (23013), Mouse Spen (56381), Rat Spen (365981), domestic guinea pig Spen (100713290), naked mole-rat Spen (101710447), Horse SPEN (100053790), cow SPEN (513692), sheep SPEN (101108848), fruit fly spen (44205), Zebrafish spen (503940) ...More
UniProtKB ID:
Gene ID:
- Human(23013) Summary: This gene encodes a hormone inducible transcriptional repressor. Repression of transcription by this gene product can occur through interactions with other repressors, by the recruitment of proteins involved in histone deacetylation, or through sequestration of transcriptional activators. The product of this gene contains a carboxy-terminal domain that permits binding to other corepressor proteins. This domain also permits interaction with members of the NuRD complex, a nucleosome remodeling protein complex that contains deacetylase activity. In addition, this repressor contains several RNA recognition motifs that confer binding to a steroid receptor RNA coactivator; this binding can modulate the activity of both liganded and nonliganded steroid receptors. [provided by RefSeq, Jul 2008]
- Mouse(56381) SPEN homolog, transcriptional regulator (Drosophila)
- Rat(365981) SPEN homolog, transcriptional regulator (Drosophila)
- domestic guinea pig(100713290) spen homolog, transcriptional regulator (Drosophila)
- naked mole-rat(101710447) spen homolog, transcriptional regulator (Drosophila)
- Horse(100053790) spen homolog, transcriptional regulator (Drosophila)
- cow(513692) spen homolog, transcriptional regulator (Drosophila)
- sheep(101108848) spen homolog, transcriptional regulator (Drosophila)
- fruit fly(44205) split ends
- Zebrafish(503940) spen homolog, transcriptional regulator (Drosophila)
- chicken(419460) spen homolog, transcriptional regulator (Drosophila)
- dog(100687765) spen homolog, transcriptional regulator (Drosophila)
- domestic cat(101082674) spen homolog, transcriptional regulator (Drosophila)
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