TMC6
transmembrane channel-like 6
Synonyms:
EV1, EVER1, EVIN1, LAK-4P
Species:
Human TMC6 (11322), Mouse Tmc6 (217353), domestic guinea pig Tmc6 (100729981), naked mole-rat Tmc6 (101696330), domestic cat TMC6 (101080340), cow TMC6 (505575), dog TMC6 (483341), sheep TMC6 (101115049), Horse TMC6 (100058089), chicken TMC6 (422089)
UniProtKB ID:
Gene ID:
- Human(11322) Summary: Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 10 transmembrane domains and 2 leucine zipper motifs. [provided by RefSeq, Jul 2008]
- Mouse(217353) transmembrane channel-like gene family 6
- domestic guinea pig(100729981) transmembrane channel-like 6
- naked mole-rat(101696330) transmembrane channel-like 6
- domestic cat(101080340) transmembrane channel-like 6
- cow(505575) transmembrane channel-like 6
- dog(483341) transmembrane channel-like 6
- sheep(101115049) transmembrane channel-like 6
- Horse(100058089) transmembrane channel-like 6
- chicken(422089) transmembrane channel-like 6
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