TPP1
tripeptidyl peptidase I
Synonyms:
CLN2, LPIC, TPP-1
Species:
Human TPP1 (1200), Mouse Tpp1 (12751), Rat Tpp1 (83534), domestic cat TPP1 (101093296), dog TPP1 (485337), chicken TPP1 (425576), naked mole-rat Tpp1 (101707185), cow TPP1 (515575), Domestic Rabbit TPP1 (100356773), domestic guinea pig Tpp1 (100733945) ...More
UniProtKB ID:
Gene ID:
- Human(1200) Summary: This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. [provided by RefSeq, Jul 2008]
- Mouse(12751) tripeptidyl peptidase I
- Rat(83534) tripeptidyl peptidase I
- domestic cat(101093296) tripeptidyl peptidase I
- dog(485337) tripeptidyl peptidase I
- chicken(425576) tripeptidyl peptidase I
- naked mole-rat(101707185) tripeptidyl peptidase I
- cow(515575) tripeptidyl peptidase I
- Domestic Rabbit(100356773) tripeptidyl peptidase I
- domestic guinea pig(100733945) tripeptidyl peptidase I
- sheep(101116858) tripeptidyl peptidase I
- Zebrafish(798347) tripeptidyl peptidase I
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ELISA
Product Number
Description
Species
Human Tripeptidyl-peptidase I ELISA, for serum, plasma and cell culture supernatants,
Species
human
Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-TPP1 antibody produced in mouse, clone 3B1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot