YARS
tyrosyl-tRNA synthetase
Synonyms:
CMTDIC, TYRRS, YRS, YTS
Species:
Human YARS (8565), Mouse Yars (107271), Rat Yars (313047), domestic guinea pig Yars (100722635), naked mole-rat Yars (101723833), Zebrafish yars (368235), chicken YARS (419666), dog YARS (478148), cow YARS (281581), domestic cat YARS (101080309) ...More
UniProtKB ID:
Gene ID:
- Human(8565) Summary: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine. [provided by RefSeq, Jul 2008]
- Mouse(107271) tyrosyl-tRNA synthetase
- Rat(313047) tyrosyl-tRNA synthetase
- domestic guinea pig(100722635) tyrosyl-tRNA synthetase
- naked mole-rat(101723833) tyrosyl-tRNA synthetase
- Zebrafish(368235) tyrosyl-tRNA synthetase
- chicken(419666) tyrosyl-tRNA synthetase
- dog(478148) tyrosyl-tRNA synthetase
- cow(281581) tyrosyl-tRNA synthetase
- domestic cat(101080309) tyrosyl-tRNA synthetase
- Horse(100070128) tyrosyl-tRNA synthetase
- Domestic Rabbit(100353312) tyrosyl-tRNA synthetase
- sheep(101111862) tyrosyl-tRNA synthetase
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