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Merck

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āļ‚āđ‰āļēāļĄāđ„āļ›āļ—āļĩāđˆ

PROBES

Custom qPCR Probes

Design and Order DNA, Locked Nucleic Acid, MGB:EDQ and BHQ Probes for qPCR

Synonym(s):

BHQ, BHQ Probes, Black Hole Quencher, Dual-Quenched Probes,, Internal-Quenched Probes, Locked Nucleic Acid probes, MGB:EDQ Probes, Probes, Real-Time PCR Probes, locked nucleic acid, qPCR assays, qPCR designs

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UNSPSC Code:
41105904




 

Dual-Labeled Probes

  • Amounts: 1, 3, 5, and 10 OD
  • Purification: HPLC
  • Sequence Lengths: 15 - 40 bases
  • Modifications: Locked Nucleic Acid and MGB:EDQ available
  • Dyes: Comprehensive offering of reporters and 3' / internal / dual quenchers
  • Quality Control: 100% mass spectrometry
  • Format: Supplied dry in amber tubes
  • Learn more

 


Molecular Beacons

  • Amounts: 1, 3, 5, and 10 OD
  • Purification: HPLC
  • Sequence Lengths: 15 - 40 bases
  • Modifications: Locked Nucleic Acid available
  • Dyes: Comprehensive offering of reporters and quenchers
  • Quality Control: 100% mass spectrometry
  • Format: Supplied dry in amber tubes
  • Learn more

LightCyclerÂŪ Probes

  • Amounts: 0.1, 0.25, 1.5, and 15 OD
  • Purification: HPLC
  • Sequence Lengths: 15 - 40 bases
  • Modifications: Locked Nucleic Acid available
  • Dyes: Probe 1 fluorescein (3â€ē end); Probe 2 phosphate (3â€ē end) and LC Red 610, 640, 670 or 705 (5â€ē end)
  • Quality Control: 100% mass spectrometry
  • Format: Supplied dry in amber tubes
  • Learn more

Locked Nucleic Acid & MGB:EDQ

  • Available with Dual-Labeled Probes and other oligos
  • Increased thermal stability and hybridization specificity
  • Easier and more specific designs for problematic target sequences
  • Learn more

Black Hole Quencherâ„Ē (BHQâ„Ē)

  • Available for all Custom qPCR Probe types
  • No native fluorescence (emits heat instead of light), resulting in lower background fluorescence
  • Increased signal-to-noise ratio, providing higher sensitivity
  • Enables a wider choice of reporters for multiplexing
  • Learn more
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āļĒāļąāļ‡āđ„āļĄāđˆāļĄāļĩāļšāļąāļāļŠāļĩāđƒāļŠāđˆāļŦāļĢāļ·āļ­āđ„āļĄāđˆ?

āļšāļ—āļ„āļ§āļēāļĄ

Regardless of next-generation sequencing (NGS) platform, universal and index adapter sequences are required for the proper assembly of sample fragments.

āđ‚āļžāļĢāļšāđāļšāļšāļ•āļīāļ”āļ‰āļĨāļēāļāļ„āļđāđˆāđ€āļ›āđ‡āļ™āđ‚āļžāļĢāļšāļŠāļ™āļīāļ”āļ—āļĩāđˆāļžāļšāļĄāļēāļāļ—āļĩāđˆāļŠāļļāļ”āļŠāļģāļŦāļĢāļąāļš qPCR āđāļĨāļ°āļĄāļąāļāļˆāļ°āđ€āļĢāļĩāļĒāļāļ§āđˆāļēāđ‚āļžāļĢāļšāđ„āļŪāđ‚āļ”āļĢāđ„āļĨāļ‹āļīāļŠ

āđ€āļ™āļ·āđ‰āļ­āļŦāļēāļ—āļĩāđˆāđ€āļāļĩāđˆāļĒāļ§āļ‚āđ‰āļ­āļ‡

Label licenses for our oligonucleotide products, including Black Hole QuencherÂŪ, BlackBerryÂŪ Quencher, and Locked Nucleic Acid (LNAÂŪ).

Custom oligo Blanket Purchase Order tracking system simplifies expenditure management for customers.

Oligo synthesis technology delivers high-quality products for research applications with full-length purity.

āļ”āļđāđ€āļ™āļ·āđ‰āļ­āļŦāļēāļ—āļĩāđˆāđ€āļāļĩāđˆāļĒāļ§āļ‚āđ‰āļ­āļ‡āļ—āļąāđ‰āļ‡āļŦāļĄāļ”

Ana F Almeida-Santos et al.
Scientific reports, 9(1), 473-473 (2019-01-27)
The absence of companion may jeopardize mental health in social animals. Here, we tested the hypothesis that social isolation impairs social recognition memory by altering the excitability and the dialog between the olfactory bulb (OB) and the dorsal hippocampus (dHIP).
Rajeev Gupta et al.
Cell stem cell, 26(4), 527-541 (2020-03-21)
Umbilical cord blood (UCB) has had considerable impact in pediatric stem cell transplantation, but its wider use is limited in part by unit size. Long-term ex vivo culture offers one approach to increase engraftment capacity by seeking to expand stem and