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Merck

G0700000

Guaifenesin

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Guaiacol glyceryl ether, 3-(o-Methoxyphenoxy)-1,2-propanediol, Glycerol guaiacolate, Guaifenesin

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About This Item

Empirical Formula (Hill Notation):
C10H14O4
CAS Number:
93-14-1
Molecular Weight:
198.22
NACRES:
NA.24
PubChem Substance ID:
329799714
UNSPSC Code:
41116107
MDL number:
MFCD00016873

Key Documents

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InChI key

HSRJKNPTNIJEKV-UHFFFAOYSA-N

SMILES string

COc1ccccc1OCC(O)CO

InChI

1S/C10H14O4/c1-13-9-4-2-3-5-10(9)14-7-8(12)6-11/h2-5,8,11-12H,6-7H2,1H3

grade

pharmaceutical primary standard

API family

guaifenesin

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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1 of 4

This Item
1301007Y0001956PHR1027
Guaifenesin European Pharmacopoeia (EP) Reference Standard

G0700000

Guaifenesin

Guaifenesin United States Pharmacopeia (USP) Reference Standard

USP

1301007

Guaifenesin

Guaifenesin for peak identification European Pharmacopoeia (EP) Reference Standard

Y0001956

Guaifenesin for peak identification

Guaifenesin certified reference material, pharmaceutical secondary standard

Supelco

PHR1027

Guaifenesin

manufacturer/tradename

EDQM

manufacturer/tradename

USP

manufacturer/tradename

EDQM

manufacturer/tradename

-

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

grade

certified reference material, pharmaceutical secondary standard

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

-

application(s)

pharmaceutical (small molecule)

format

neat

format

neat

format

neat

format

neat

API family

guaifenesin

API family

guaifenesin

API family

guaifenesin

API family

guaifenesin

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

storage temp.

2-30°C

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Guaifenesin EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Robert R Fayzullin et al.
Journal of pharmaceutical sciences, 103(10), 3176-3182 (2014-08-06)
The solubility of 3-(2-methoxyphenoxy)-propane-1,2-diol, the well-known chiral drug guaifenesin 1, in water has been investigated by means of polythermal and isothermal approaches. It was found that the solubilities of racemic and enantiomeric diols rac- and (R)-1 depend strongly on temperature.
William Storms et al.
Current allergy and asthma reports, 9(2), 101-106 (2009-02-13)
Mucus in the airways is a complex mixture of water, lipids, glycoproteins, sugars, and electrolytes that serves as a lubricant for the epithelium. The efficient flow of respiratory mucus is a first level of immune defense that requires an appropriate
Stephen Bennett et al.
Journal of alternative and complementary medicine (New York, N.Y.), 10(6), 967-969 (2005-01-28)
Ephedrine and guaifenesin are herbal supplements that have experienced increased use over the past decade. Ephedrine has been used as a stimulant and weight-loss product, guaifenesin as an expectorant and cough suppressant; both are found in combination in many antitussives
Clinical inquiries. Is guaifenesin safe during pregnancy?
Roberto Silva et al.
The Journal of family practice, 56(8), 669-670 (2007-08-03)
Brian C Gilger et al.
Veterinary ophthalmology, 17 Suppl 1, 23-30 (2013-08-06)
To describe the use of episcleral silicone matrix cyclosporine (ESMC) drug delivery devices in horses with immune-mediated keratitis (IMMK) with evaluation of tolerability and efficacy in long-term control of inflammation. Retrospective study. ESMC implants (1.2 cm length, 30% wt/wt cyclosporine
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