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C9008

Sigma-Aldrich

p-Coumaric acid

≥98.0% (HPLC)

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Synonym(s):
trans-4-Hydroxycinnamic acid
Linear Formula:
HOC6H4CH=CHCO2H
CAS Number:
Molecular Weight:
164.16
Beilstein:
2207383
MDL number:
PubChem Substance ID:
NACRES:
NA.47

Assay

≥98.0% (HPLC)

form

powder

color

white to yellow

mp

214 °C (dec.) (lit.)

solubility

ethanol: 50 mg/mL

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

OC(=O)\C=C\c1ccc(O)cc1

InChI

1S/C9H8O3/c10-8-4-1-7(2-5-8)3-6-9(11)12/h1-6,10H,(H,11,12)/b6-3+

InChI key

NGSWKAQJJWESNS-ZZXKWVIFSA-N

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This Item
H1252722812A1028
vibrant-m

C9008

p-Coumaric acid

vibrant-m

H1252

Homovanillic acid

vibrant-m

722812

p-Coumaric acid-1,2,3-13C3

storage temp.

room temp

storage temp.

room temp

storage temp.

−20°C

storage temp.

room temp

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

-

application(s)

diagnostic assay manufacturing
hematology
histology

assay

≥98.0% (HPLC)

assay

>99% (TLC)

assay

99% (CP)

assay

≥97% (HPLC)

form

powder

form

powder

form

solid

form

powder

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

Application

p-Coumaric acid has been used as a component of chemiluminescent substrate for protein detection in western blotting.

Biochem/physiol Actions

In western blot, p-coumaric is also used as an enhancer in chemiluminescent substrate.
Hydroxycinnamic acid found in many fruits and vegetables.

Other Notes

Predominantly trans isomer.

related product

Product No.
Description
Pricing

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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p-Coumaric acid kills bacteria through dual damage mechanisms.
Zaixiang L, et al.
Food Control, 25, 550-554 (2012)
A cost effective non-commercial ECL-solution for Western blot detections yielding strong signals and low background.
Haan C and Behrmann I
Journal of Immunological Methods, 318, 11-11 (2007)
Inflammation triggers high mobility group box 1 (HMGB1) secretion in adipose tissue, a potential link to obesity.
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TGF-beta receptor levels regulate the specificity of signaling pathway activation and biological effects of TGF-beta.
Rojas A, et al.
Biochimica et Biophysica Acta, 1793, 1165-1173 (2009)
Enhanced chemiluminescence (ECL) for routine immunoblotting: An inexpensive alternative to commercially available kits.
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Protocols

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