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HomeWebinarsKey Considerations and Learnings to Run a Fully Connected and Continuous Benchtop Bioprocess

Key Considerations and Learnings to Run a Fully Connected and Continuous Benchtop Bioprocess



WEBINAR

As integrated and continuous manufacturing is increasingly prevalent, the implementation of connected operations for the biopharmaceutical industry is still a challenge. In this work, we executed a continuous mAb production process, operating a perfusion bioreactor integrated with continuous downstream technologies for three days of operation and a digital infrastructure allowing collaboration and data sharing. The system provides benefits such as increased productivity, reduced risk of errors, improved data management, alarm management, and operations. Ultimately, we highlight how digital transformation allows us to remain competitive and deliver cutting-edge products in the industry.

In this webinar, you will learn:

  • The key factors for successful development of integrated continuous biomanufacturing operations
  • The challenges of implementing continuous processing at the bench scale
  • The importance of embracing digital transformations and the benefits of improved data management

Speakers

James Angelo

James Angelo

Merck

R&D Manager - PAT & Digital Applications

James Angelo is an R&D manager in PAT & digital applications, where his team focuses on the implementation and integration of new PAT tools and analytical capabilities into intensified biologics processes. He joined Merck in July 2022 from Bristol Myers Squibb, where he led teams in late-stage purification process development and technology transfer of continuous downstream operations into cGMP manufacturing.

Jean-Luc Gerling

Jean-Luc Gerling

Merck

R&D Manager in Digital Innovation

As an R&D manager in digital innovation, Jean-Luc Gerling leads his team in the development of solution architecture for network and infrastructure, cybersecurity and compliance. He joined Merck in September 2016 from Eli Lilly, where he acquired extensive experience across pharmaceutical and life science Industries. At Eli Lilly, he has worked on solution building for MES, SCADA, IT INFRASTRUCTURE, and process automation and instrumentation. He has helped bring innovative control process systems to production by applying the newest standard integration from bioprocessing to packaging.

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