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NF-κB and Inflammation
Chronic inflammation is an underlying factor in the development and progression of many of the chronic diseases of aging, such as arthritis, atherosclerosis, diabetes, and cancer.
Angiogenesis Assays
Cell based angiogenesis assays to analyze new blood vessel formation for applications of cancer research, tissue regeneration and vascular biology.
Immunohistochemistry Applications in Gastrointestinal Cancer
Colorectal cancer is the third most common cancer in both men and women. An estimated 136,000 cases of colorectal cancer are expected to occur in 2016.
3D Neurosphere Culture Media
3D neurosphere culture protocol to expand human U-87 MG glioblastoma cells in serum-free/xeno-free stem cell culture media. Explore over 350 PromoCell products on Sigma.com.
DNA Damage Response (DDR) Pathway
Explore key targets of cancer research and cell signaling research with the DNA damage response (DDR) pathway and do a deep dive into ATM, ATR, and p53 mechanisms involved in DNA damage checkpoints.
Epigenetics Overview
Epigenetics is a term coined to describe changes that are not mutation based but can still be passed on from generation to generation. Genes that are activated or repressed without any change in DNA sequence are epigenetically controlled. Epigenetic modifications
Autophagy in Cancer Promotes Therapeutic Resistance
We presents an article on Autophagy in Cancer Promotes Therapeutic Resistance
Cancer Stem Cell Proliferation in Human Prostate and Breast Cancer Cell Lines Utilizing a New Defined Serum-Free 3D Spheroid Media
Serum-free defined cancer stem cell media used to grow and expand cancer cells in 3D tumorsphere aggregates.
Apoptosis Assays
Cellular apoptosis assays to detect programmed cell death using Annexin V, Caspase and TUNEL DNA fragmentation assays.
5 Reasons Cancer Researchers Adopt 3D Cell Culture: A Review of Recent Literature
Numerous cancer model systems are available to investigate disease mechanisms and to screen therapies. While all of the models have contributed critical information about cancer biology.
Co-culture of Tumor and Stromal Cells in TrueGel3D™ Hydrogels
TrueGel3D™ synthetic hydrogel can be used to study co-culture of tumor and stromal cells.
Epidermal Growth Factor Receptor (EGFR) Signaling
Review EGF/EGFR signaling (epidermal growth factor receptor) and find links to related products.
Tissue Markers for Cancer Diagnostics
Immunohistochemistry (IHC) represents an indispensable tool in cancer diagnostics.
Long-Term Live Cell Tracking of Cancer and Stem Cells Using a Biocompatible Fluorescent Nanoparticle Based Upon Aggregation Induced Emission (AIE Dot) Nanotechnology
Biocompatible organic fluorescent nanoparticles (AIE Dots) that can be used to label cells and vasculature for long-term live cell tracking and tracing experiments.
Hypoxia Detection Assays
Hypoxia detection assays to measure oxygen levels in both live and fixed cells and tissues.
Primary Cell Culture Basics
Overview of primary cells and media usage in biomedical culture applications highlights differences from cell lines.
Fatty Acid Synthesis in Cancer Cells
Fatty acid synthesis supports cancer cell proliferation, essential for membrane generation, protein modification, and bioenergetics.
Folic Acid Metabolism in Cancer
Cancer research innovations address the complexity of the disease, providing advanced technologies for varied applications.
Autophagy Mitophagy in Tumor Cell Survival Death
Autophagy is a regulated process involved in cell growth, development, and recycling of cytoplasmic components in cells.
Applications of Cytokines and Growth Factors in Cancer Research
Applications of Cytokines and Growth Factors in Cancer Research
DNA Damage and Repair
DNA damage and repair mechanism is vital for maintaining DNA integrity. Damage to cellular DNA is involved in mutagenesis, the development of cancer among others.
Superoxide Dismutase
Enzyme Explorer Product Application Index for Superoxide Dismutase offered by us online. Superoxide Dismutase (SOD) catalyzes the reduction of superoxide anions to hydrogen peroxide.
Fibroblast Growth Factor Family (FGF)
Fibroblast growth factors in cell culture and various growth factors for your research
Carcinogenesis and Epigenetics
Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete.
Immunohistochemistry: Current Applications in Breast Cancer
Immunohistochemistry (IHC) is used to characterize intracellular proteins or various cell surfaces in all tissues. Individual markers or more often panels of various marker proteins can be used to characterize various tumor subtypes, confirm tissue of origin, distinguish metastatic from
Dynamic Live Cell Imaging of Caspase Mediated Apoptosis and Cellular Hypoxia in Lymphocytes and Cancer Cells Using the CellASIC® ONIX2 Microfluidic Platform
Application note on how the CellASIC® ONIX2 microfluidic system can be used to analyze caspase-3 mediated apoptosis/cell death and cellular hypoxia in live immune and cancer cell lines.
TokeOni: Properties and Applications
Bioluminescence imaging (BLI) systems allows for high-sensitive and noninvasive monitoring of cell proliferation, activity of signaling pathways and protein-protein interactions in living tissues.
Cancer Stem Cells: Targets for Cancer Therapy
Cancer stem cell media, spheroid plates and cancer stem cell markers to culture and characterize CSC populations.
Prestige Antibodies® in Breast Cancer Research
Browse Human Protein Atlas; Prestige Antibodies®; Polyclonals and Monoclonals; Clinical Markers; Antibodies used in breast cancer research.
Angiostatin and Endostatin: Key Players in a Dual Threat Approach to Cancer Treatment
Anticancer drugs development - natural and synthetic angiogenesis inhibitors.
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