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Poly(Amino Acid) Block Copolymers for Drug Delivery and other Biomedical Applications
Humankind has utilized protein materials throughout its existence, starting with the use of materials such as wool and silk for warmth and protection from the elements and continuing with the use of recombinant DNA techniques to synthesize proteins with unique
RESOMER® - Biodegradable Polymers for Sutures, Medical Devices, Drug Delivery Systems and Tissue Engineering
Interest in utilizing biodegradable polymers for biomedical applications has grown since the 1960s.
Polymersomes for Drug Delivery
The development of drugs that target specific locations within the human body remains one of the greatest challenges in biomedicine today.
Chitosan-based Biomaterials
Chitin, a natural polysaccharide, is the second most abundant natural biopolymer in the world, after cellulose.
Photo-Crosslinkable Gelatin Hydrogel: Versatile Materials for (High Resolution) Additive Manufacturing
Discussion of synthetic modifications to gelatin, improving the three-dimensional (3D) print resolution, and resulting material properties.
Poly(N-isopropylacrylamide)-based Smart Surfaces for Cell Sheet Tissue Engineering
Tissue engineering has become a key therapeutic tool in the treatment of damaged or diseased organs and tissues, such as blood vessels and urinary bladders.
Therapeutic Nanoparticles Harness Myeloid Cells for Brain Tumor-Targeted Delivery and Immunomodulation
Immunosuppressive tumor-associated myeloid cells (TAMC) are responsible for glioblastoma (GBM) resistance to immunotherapies and existing standard of care treatments. This mini-review highlights recent progress in implementing nanotechnology in advancing TAMC-targeted therapies for GBM.
Microfluidics for Nanoencapsulation of Nucleic Acids Using Polymeric Carriers
Microfluidic assembly can efficiently overcome the general disadvantages of polyamine nanoencapsulation of nucleic acids, such as a less defined morphology and composition, polydispersity, and poor reproducibility.
Protein- and Peptide- Polymer Conjugates by RAFT Polymerization
The modification of biomacromolecules, such as peptides and proteins, through the attachment of synthetic polymers has led to a new family of highly advanced biomaterials with enhanced properties.
Tailoring Collagen-Based Matrices for Regenerative Medicine and Tissue Engineering
Collagen molecules play a critical role in tissue architecture and strength, and in cell-matrix interactions as insoluble ligands to regulate the diverse phenotypic activities of cells.
Preparation of Chitosan Microparticles by Spray Drying
Carcinogenic compounds in elastomers: 1,3-butadiene and isoprene used in elastomer manufacturing, classified as carcinogenic by IARC.
Functional Polymers for Biomedical Apps
Microparticles in drug delivery: Study on controlling chitosan microparticle size and distribution, exploring encapsulation of BSA and TPP cross-linker.
Poly(Glycerol Sebacate) in Tissue Engineering
Synthetic aliphatic polyesters dominate resorbable biomaterials in clinical use.
PEGylation Tools
Polyethylene glycol (PEG) reagents offer favorable characteristics for various applications, including biocompatibility and solubility.
Biogelx™ Peptide Bioinks
Biogelx™ peptide products excel in 2D/3D cell culture; mimic tissue properties for biomedical/pharmaceutical innovation globally.
Strat-M® Membrane for Sunscreen Formulation Testing
Strat-M synthetic membrane model is an alternative to human skin for testing the effectiveness of skin care actives.
Photocrosslinkable Hydrogels for 3D Cell Culture
Methacrylated hydrogels enable 3D cell culture scaffolds and bioprinting using light crosslinking.
Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture
Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic
Poly(ethylene glycol) (PEG) and Synthetic PEG Derivatives for Tissue Engineering and Cell Delivery
Highlighting new synthetic modifications of PEG to improve the mechanical properties and degradation of resulting hydrogels in tissue engineering applications.
Bioprinting for Tissue Engineering and Regenerative Medicine
In the past two decades, tissue engineering and regenerative medicine have become important interdisciplinary fields that span biology, chemistry, engineering, and medicine.
Chemistry in (Bio)Materials Science
"Click" Chemistry in (Bio)Materials Science
Biomedical Implant Devices Fabricated from Low Young’s Modulus Titanium Alloys Demonstrating High Mechanical Biocompatibility
Biomedical implants are essentially foreign substances within the human body that must survive many years’ exposure to demanding mechanical and physiological conditions. Despite these challenges, metal implants have been widely used to substitute for or rebuild hard tissues such as
Poly(2-Oxazoline)s: The Versatile Polymer Platform for Biomedicine
The introduction of polymers into the biomedical field has opened new avenues in tissue engineering, implant design, biosensing, and drug delivery.
Controlled Fabrication Methods for Tissue Engineering Constructs
Highlighting existing and novel fabrication methods for both, solid and hydrogel-based scaffold for tissue engineering applications.
Dendrons and Hyperbranched Polymers: Multifunctional Tools for Materials Chemistry
Dendrons in nanomaterials - Find features and benefits of polyester dendrons and hyperbranched polymer products.
3D Printing Graphene Ink: Creating Electronic and Biomedical Structures and Devices
Since its discovery little more than a decade ago,1 the two-dimensional (2D) allotrope of carbon—graphene—has been the subject of intense multidisciplinary research efforts.
Stimuli-Responsive Materials as Intelligent Drug Delivery Systems
By altering the physicochemical properties, smart or intelligent drug delivery systems can be designed to deliver therapeutic molecules on-demand. Learn more about the application of stimuli-responsive materials in drug delivery.
RAFT Polymerization
RAFT polymerization offers living characteristics to radical polymerization, contributing versatility to reversible deactivation radical polymerization methods.
New Multi-Dendrimer Platforms for Supramolecular Assembly
Dendrimers, polymer nanostructures, are synthesized for specific purposes by manipulating critical nanoscale design parameters (CNDPs).
Electrospinning: Enabling Nanostructured Materials
Electrospinning technique applications discussed, emphasizing control of nanofibers and assembly into 3D architectures.
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