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Merck

ABCC2

ATP-binding cassette, sub-family C (CFTR/MRP), member 2

同義詞:
ABC30, CMOAT, DJS, MRP2, cMRP
物種:
Human ABCC2 (1244), Mouse Abcc2 (12780), Rat Abcc2 (25303), sheep ABCC2 (101119776), Horse ABCC2 (100060654), naked mole-rat Abcc2 (101716089), domestic guinea pig Abcc2 (100718828), cow ABCC2 (520925), domestic cat ABCC2 (101085924), dog ABCC2 (403632) ...更多
UniProtKB ID:
Q92887, B2RMT8, Q14022, Q5T2B1, Q92500, Q92798, Q99663, Q9UMS2
基因 ID:
  • Human(1244) Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia. [provided by RefSeq, Jul 2008]
  • Mouse(12780) ATP-binding cassette, sub-family C (CFTR/MRP), member 2
  • Rat(25303) ATP-binding cassette, subfamily C (CFTR/MRP), member 2
  • sheep(101119776) ATP-binding cassette, sub-family C (CFTR/MRP), member 2
  • Horse(100060654) ATP-binding cassette, sub-family C (CFTR/MRP), member 2
  • naked mole-rat(101716089) ATP-binding cassette, sub-family C (CFTR/MRP), member 2
  • domestic guinea pig(100718828) ATP-binding cassette, sub-family C (CFTR/MRP), member 2
  • cow(520925) ATP-binding cassette, sub-family C (CFTR/MRP), member 2
  • domestic cat(101085924) ATP-binding cassette, sub-family C (CFTR/MRP), member 2
  • dog(403632) ATP-binding cassette, sub-family C (CFTR/MRP), member 2
  • chicken(423828) ATP-binding cassette, sub-family C (CFTR/MRP), member 2
  • Zebrafish(393561) ATP-binding cassette, sub-family C (CFTR/MRP), member 2

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Antibodies

產品編號
描述
物種活性
應用
MAB4148
Anti-MRP2 Antibody, clone M2 I-4, culture supernatant, clone M2 I-4, Chemicon®,
物種活性
human
應用
immunocytochemistry
immunohistochemistry
western blot
SAB1403681
Monoclonal Anti-ABCC2 antibody produced in mouse, clone 2H6, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
immunofluorescence
western blot
MAB4150
Anti-MRP2 Antibody, CT, clone M2 III-6, culture supernatant, clone M2 III-6, Chemicon®,
物種活性
human
應用
immunocytochemistry
immunohistochemistry
western blot
M8316
Anti-MRP2 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物種活性
human, rat
應用
immunofluorescence
western blot

Kits

產品編號
描述
物種
MAK161
多药耐药分析试剂盒, (Fluorometric MDR Assay),
物種
human, mouse, rat

Proteins

產品編號
描述
物種
SBPE03
SB-MRP2-Sf9-PREDEASY-ATPase试剂盒, membrane based kit for Human MRP2 ATPase Transport Assays,
物種
human