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Merck

AKTIP

AKT interacting protein

同義詞:
FT1, FTS
物種:
UniProtKB ID:
基因 ID:
  • Human(64400) Summary: The mouse homolog of this gene produces fused toes and thymic hyperplasia in heterozygous mutant animals while homozygous mutants die in early development. This gene may play a role in apoptosis as these morphological abnormalities are caused by altered patterns of programmed cell death. The protein encoded by this gene is similar to the ubiquitin ligase domain of other ubiquitin-conjugating enzymes but lacks the conserved cysteine residue that enables those enzymes to conjugate ubiquitin to the target protein. This protein interacts directly with serine/threonine kinase protein kinase B (PKB)/Akt and modulates PKB activity by enhancing the phosphorylation of PKB's regulatory sites. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
  • Mouse(14339) thymoma viral proto-oncogene 1 interacting protein
  • Rat(291906) AKT interacting protein
  • chicken(415720) AKT interacting protein
  • dog(478126) AKT interacting protein
  • naked mole-rat(101700642) AKT interacting protein
  • domestic cat(101095626) AKT interacting protein
  • cow(540462) AKT interacting protein
  • sheep(101114547) AKT interacting protein
  • Zebrafish(378716) akt interacting protein
  • domestic guinea pig(100715546) AKT interacting protein

Custom & Knockdown Gene Products

Antibodies

產品編號
描述
物種活性
應用
Monoclonal Anti-FTS antibody produced in mouse, clone 2A11, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
western blot
Anti-AKTIP antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
western blot