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Merck

ERBB3

v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3

同義詞:
ErbB-3, HER3, LCCS2, MDA-BF-1, c-erbB-3, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3, p85-sErbB3
物種:
Human ERBB3 (2065), Mouse Erbb3 (13867), Rat Erbb3 (29496), cow ERBB3 (785655), dog ERBB3 (481105), domestic guinea pig Erbb3 (100712946), chicken ERBB3 (693245), sheep ERBB3 (101103889), Domestic Rabbit ERBB3 (100008807), Horse ERBB3 (100059216) ...更多
UniProtKB ID:
P21860, A8K6L6, B4DIK7, B4DV32, E9PDT8, Q9BUD7
基因 ID:
  • Human(2065) Summary: This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported, but they have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
  • Mouse(13867) v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
  • Rat(29496) v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
  • cow(785655) v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
  • dog(481105) v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
  • domestic guinea pig(100712946) v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
  • chicken(693245) v-erb-b2 erythroblastic leukemia viral oncogene homolog 3
  • sheep(101103889) v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
  • Domestic Rabbit(100008807) v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
  • Horse(100059216) v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
  • domestic cat(101085388) v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
  • naked mole-rat(101721671) v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)

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ELISA

產品編號
描述
物種
RAB0174
人ErbB3 / HER3 ELISA试剂盒, for serum, plasma, cell culture supernatant and urine,
物種
human

Antibodies

產品編號
描述
物種活性
應用
05-390
抗-erbB-3/HER-3抗体，克隆2F12, clone 2F12, Upstate®, from mouse,
物種活性
bovine, human, mouse, rat
應用
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
SAB4300580
抗-ERBB3 (Ab-1328) 兔抗, affinity isolated antibody,
物種活性
human, mouse, rat
應用
immunohistochemistry
western blot
SAB4500792
Anti-HER3 antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
western blot
WH0002065M1
Monoclonal Anti-ERBB3 antibody produced in mouse, clone 2E9, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
western blot
MAB4023
Anti-c-erbB-3 Antibody, cytoplasmic domain, clone RTJ2, clone RTJ2, Chemicon®, from mouse,
物種活性
human
應用
ELISA
immunohistochemistry
immunoprecipitation (IP)
western blot