F7
coagulation factor VII (serum prothrombin conversion accelerator)
同義詞:
SPCA
物種:
Human F7 (2155), Mouse F7 (14068), Rat F7 (260320), naked mole-rat F7 (101706917), domestic guinea pig F7 (100727155), fruit fly f7 (5657732), Zebrafish f7 (114423), chicken F7 (395086), dog F7 (607661), domestic cat F7 (101090581) ...更多
UniProtKB ID:
基因 ID:
- Human(2155) Summary: This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagulopathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
- Mouse(14068) coagulation factor VII
- Rat(260320) coagulation factor VII (serum prothrombin conversion accelerator)
- naked mole-rat(101706917) coagulation factor VII (serum prothrombin conversion accelerator)
- domestic guinea pig(100727155) coagulation factor VII (serum prothrombin conversion accelerator)
- fruit fly(5657732) f7
- Zebrafish(114423) coagulation factor VII
- chicken(395086) coagulation factor VII (serum prothrombin conversion accelerator)
- dog(607661) coagulation factor VII (serum prothrombin conversion accelerator)
- domestic cat(101090581) coagulation factor VII (serum prothrombin conversion accelerator)
- cow(617960) coagulation factor VII (serum prothrombin conversion accelerator)
- sheep(101118369) coagulation factor VII (serum prothrombin conversion accelerator)
- Domestic Rabbit(100009399) coagulation factor VII (serum prothrombin conversion accelerator)
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Antibodies
產品編號
描述
物種活性
應用
抗-因子VII抗体，小鼠单克隆, clone HVII-1, purified from hybridoma cell culture,
物種活性
human
應用
ELISA
western blot
western blot