生物製程用色譜系統
一次性與可重複使用色譜系統是成功分離珍貴分子的關鍵要素。從中試到工業規模，我們的系統專為提供穩健、一致的性能而設計，同時具備您所需的處理靈活性。 我們同時提供無可匹敵的色譜樹脂與膜產品組合，並配備頂尖的應用技術與驗證支援。憑藉這套完整的產品體系，我們持續協助您提升生產力與製程效率。專業團隊將為您量身推薦最適切的色譜製程解決方案。
產品
Mobius® 多柱捕集系統
Mobius® 多柱捕集系統是實現連續封閉捕集色譜的完全自動化一次性解決方案。該系統可根據變化的色譜柱負荷、衝浪進料槽負荷及樹脂性能監測，實時管理製程參數。結合在線稀釋功能與直觀軟體，此三柱系統能全面掌控您的分批進料或灌流生物製程中的捕集步驟。 Mobius® 多柱捕集系統適用於 50 公升至 2000 公升的生物反應器體積。深入了解多柱色譜技術。
相關資源
- Application Note: Multi-Column Chromatography for Efficient Polishing Purification
The studies in this application note focus on Ion Exchange (IEX) chromatography in bind/elute mode using the Mobius® Multi Column Capture system.
- Application Note: Efficient Protein A Capture in Intensified Processes: Process Characterization and Scalability
Assess the efficiency of continuous mAb capture from a clarified and filtered harvest cell culture fluid (HCCF), using the Mobius® Multi Column Capture system and evaluate process scalability.
- In-Line Dilution Capabilities of Mobius® Multi Column Capture System for Effective Buffer Management Strategies
Enhancing Intensified Chromatography Performance through Automated Buffer Dilution
- Application Note: Process Development and Scale-Up Strategy for the Mobius® Multi Column Capture System
A methodology for developing and scaling up a process for a multi-column capture operation using the Mobius® Multi Column Capture.
- Data Sheet: Mobius® Multi Column Capture System
The Mobius® Multi Column Capture system is designed as a fully automated, single-use solution to operate continuous closed capture chromatography.
- Data Sheet: Mobius® Chrom Systems
The Mobius® Chrom systems are a flexible, automated, single-use chromatography systems that enable consistent and reliable separation and purification.
- Application Note: Multi-Column Capture
Prototype Tests for Monoclonal Antibody Capture During Project nextBioPharmDSP (Horizon 2020).
- Technical Brief: Mobius® Breez Microbioreactor
Mixing and Gas Transfer in the Mobius® Breez Microbioreactor – How It Works?
- Spare Parts List: Mobius® Multi Column Capture System
To help you select and manage the spare parts required for your system, our experts have performed a risk assessment to determine which parts to keep in stock.
- Performance Guide: Mobius® Multi Column Capture System
The purpose of this document is to describe the performance of the Mobius® Multi Column Capture system and highlight the working principles of its innovative features.
- Data Sheet: CoPrime® Biochromatography Process-Scale System
Fully automated, configurable systems for biopharmaceutical manufacturing and cGMP process scale applications.
- Poster: Horizon 2020 - Fully Connected Single-use Downstream Platform for mAb Production
Within the biopharmaceutical industry, there is a significant shift toward higher productivity processes resulting in improved economics without compromising robustness. Therefore, integrated continuous production technologies are of greatest interest.
- Brochure: Process Development and Drug Manufacturing: Support Services
We provide comprehensive services for drug development and manufacturing, including technical and regulatory expertise and process development support.
- Application Note: Implementation of Multi-Column Chromatography Systems
The Multi-Column Capture (MCC) System enables efficient primary capture through three column operation, supporting continuous feedstream processing.
- Performance Guide: Mobius® Chrom 10 System
Discover Mobius® Chrom 10 system’s key performance highlights for scalable chromatography in clinical and commercial purification.
- Performance Guide: Mobius® Chrom 2 System
Discover the Mobius® Chrom 2 system, fully automated with operational flexibility, designed to reduce cross-contamination in scalable chromatography.
相關線上研討會
多柱色譜法是一種生物製程技術，其原理是將多根色譜柱串聯裝載，隨後循環進行洗脫、再生與平衡操作。
新型蛋白A親和膜的優勢，作為高產能、真正一次性使用的色譜平台，用於強化單株抗体的純化。
CEX流過式前端層析法用於去除單株抗體聚集物，以及影響此類聚集物去除效果的條件。
疫苗純化用客製化親和層析技術綜覽
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