With plug ‘n play and linearly scalable Pellicon® Capsules for gene therapy and vaccine production.
Our Pellicon® Capsules are a true single-use solution for your TFF challenges. Designed for efficient single-use UF/DF, the Pellicon® Capsule is a first-of-its-kind spiral-wound TFF filter engineered to provide you with performance consistency and linear scalability for reliable process development and predictable scale-up at any stage of your gene therapies and vaccines.
Its plug ‘n play holderless format provides fast and easy installation, as well as self-containment for those processes requiring additional safety. The capsules are gamma sterilized and can integrate into our TFF systems from process development to process scale. With optimum feed channel design, the capsules perform with high flux to meet your concentration targets with speed.
Comparison of initial operating flux performance for flatsheet and hollow fiber filters and operating systems for 100 and 300 kDa NMWL. For TMP control (one pump), initial flux is the flux at optimal TMP. For permeate control (two pump), initial flux is 50% of the critical flux. The higher flux provided by capsules and cassettes result in faster processing time or reduced membrane area requirements.
Inventory is Limited. Pellicon® Capsules size 0.1 m2 with Ultracel® membrane 100 kD and 300 kD only available for this offer.
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Product Overview: Ultrafiltration/Diafiltration (UF/DF) of Adeno-Associated Viruses (AAV) with Pellicon® Capsules and Pellicon® XL 50 Cassettes
Technical Article: Tangential Flow Filtration in Downstream Bioprocessing
Technical Article: Single-Pass Tangential Flow Filtration Implementation and Scaling
Technical Article: Tangential Flow Filtration in the Antibody Drug Conjugate (ADC) Manufacturing Process
Podcast Transcript: Interview - Shear ignorance? Think again: breaking the perception of shear within viral vector manufacturing
Application Note: Pellicon® Capsules versus Hollow Fibers for Ultrafiltration/Diafiltration (UF/DF) in Viral Gene Therapy Manufacturing
Evaluation of TFF Operating Control Strategies and Scalability for Viral Vector Process Development
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