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MilliporeSigma

Protein Prep Begins with Precision

Explore our comprehensive offering of enzymes, protein reagents, and protein kits.


New Protein Sample Prep Products

Whether you are working in biomarker discovery, proteomics, recombinant protein development, or pharmaceutical analysis, it can be difficult to easily find the protein sample prep products you need. This page has our newest product releases, conveniently organized into multiple applications and focus areas. Some highlights include:

  • Convenient Proximity Proteomics: Recombinantly expressed Protein A-TurboID fusion protein allows Protein A-Turbo to bind IgG and enzymatically biotinylate proximal proteins
  • High Sensitivity: Detect and quantify protease activity with no separation or precipitation steps using the Red Protease Detection Kit
  • Glyco Probing: Tightly bind densely O-linked mucin glycoproteins with Mucin Probe, StcE and use its FLAG® tag or biotin conjugate for further analysis
  • Efficient Sample Prep: Get better catalysis of steroidal sulfate esters with Enhanced Recombinant Arylsulfatase when prepping urine metabolite samples for HPLC and/or Mass Spec analysis
  • High Purity Lectin: Remove the risk of erythroagglutinin (PHA-E) contamination with the recombinant Leucoagglutinin from P. vulgaris that contains only the leucoagglutinin (PHA-L) isolectin

Take the guesswork out of finding new products for your research. Check out our latest protein products and get what you need. 

Product No.Product Description
SAE1000SARS-CoV-2 (COVID-19) RBD (spike protein)
SAE0199SARS-CoV-2 (COVID-19) RBD (Spike Protein), Biotin Tagged
SAE0172Mpro, 3CL Protease from coronavirus SARS-COV-2 (lyophilized powder)
SAE01803CL, Mpro protease fluorogenic substrate peptide
SAE0171Angiotensin Converting Enzyme (ACE)-2
CS2000SARS-CoV-2 (COVID-19) Inhibitors Screening Kit
Product No.Product Description
SAE0213Arylsulfatase, Enhanced, Recombinant 
SRE0093
Recombinant Beta-Glucuronidase from Limpets
SRE0095Fast recombinant Beta-Glucuronidase from Limpets
SAE0157Potassium Acetate Buffer Solution for SRE0095
SRE0103MS Beta-Glucuronidase (in solution, buffered in volatile salts for Mass Spec)
Product No.Product Description
SAE0214Leucoagglutinin from P. vulgaris, Recombinant
SAE0212Mucin Probe, StcE 
SAE0202Mucinase, StcE (Mucin specific protease)
EMS0001PNGase Fast Kit
G1549PNGase F, Elizabethkingia meningoseptica, glycerol solution
F8435PNGase F, Elizabethkingia meningoseptica, powder
SAE0093Beta-1, 4 galactosyl Transferase 1
SAE0090Sialyl Transferase 2,6 GAL
SAE0071HIV-1 GP120 Protein
SAE0116Heparanase-1 pre-activated human
Product No.Product Description
PPC2020ReadyShield® Protease and Phosphatase Inhibitor Cocktail, General Use
P0001ReadyShield® Phosphatase Inhibitor Cocktail, General Use
PIC0002ReadyShield® Protease inhibitor cocktail, mammalian cell and tissue extract use
PIC0001ReadyShield® Protease Inhibitor Cocktail, for Fungal & Yeast samples
PIC0004ReadyShield® Protease inhibitor cocktail, for use in purification of Histidine-tagged proteins
PIC0007ReadyShield® Protease Inhibitor Cocktail, for use in Mass Spec workflows
PIC0005ReadyShield® Protease inhibitor cocktail for plant cell and tissue extracts
PIC0006ReadyShield® Protease inhibitor cocktail for use in tissue culture media
Product No.Product Description
CS0013Red Protease Detection Kit
CS0012ATP bioluminescence detection kit
SAE0198Calprotectin
CS0005Cholesterol Quantification Assay Kit
SAE0193Extracellular Vesicle standards, fluorescent (exosomes)
SAE0088Filipin Complex Ready Made Solution
SAE0087Filipin III Ready Made Solution
CS0011Phospholipase C (PLC) Activity Assay Kit
CS0009Superoxide Dismutase, SOD, Activity Assay Kit
CS0001Phospholipid Quantification Assay Kit
CS0002Angiotensin I converting enzyme (ACE1) Assay Kit
CS0003Acetylcholinesterase activity assay kit
CS0006Soluble collagen quantification assay kit
CS0007Methanol Quantification Assay Kit
CS0008Enzymatic Protein Biotinylation Kit
MSG1000VD-DDC Mass Spect Gold® Serum
MSG2000VD-DC Mass Spect Gold® Serum
MSG3000DDC Mass Spect Gold®
MSG4000DC Mass Spect Gold® Serum
UPS3Universal Protein Standard for Mass Spec
SAE0148Fusayama/Meyer Artificial Saliva
SAE0149Artificial Saliva
Product No.Product Description
SAE0194Purified 3xFLAG® peptide
B3111ANTI-FLAG® M2 antibody, Bioreactor grade, Mouse monoclonal
SAE0197Anti-HA magnetic beads
SAE0201Anti-c-Myc magnetic beads
SAE0203Anti-V5 magnetic beads
E2513Extravidin® -Agarose, high binding
SAE0094SAvPhire Monomeric Streptavidin
SAE0067SUMO Protease
SAE0101SUMO Protease, Biotin tagged
SAE0195IceTEV Protease (low temp)
SAE0147Thrombin protease, biotin-tagged
T4455TEV protease
SAE0045HRV-3C protease
SAE0110HRV-3C protease, biotin tagged
Product No.Product Description
PAT001Protein A-Turbo - Proximity Biotinylation Enzyme 
SAE0196Achromopeptidase from bacteria (DNA free)
LYSC9000EndoLysC, in solution
LYSC9001EndoLysC, powder
EMS0008LysargiNase
SAE0200Lytic Enzyme Mixture for Fungal & Yeast samples (DNA Free)
EMS0006Recombinant Trypsin
EMS0007Recombinant Trypsin Dimethylated
EMS0004SOLu-Trypsin (proteomics grade in solution)
EMS0005SOLu-Trypsin Dimethylated (proteomics grade in solution)
MSKT0002SOLu-Trypsin Rapid Digestion Kit (proteomics grade in solution)
S2577Streptavidin High Capacity Coated Plates

For additional related reagents and resource needs, please explore our Proteins and Enzymes resource hub.

You can also download our infographics on Protein Extraction and Protein Tags for some quick tips to enhance your protein sample prep.


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