Prof. Bruce Lipshutz and co-workers have developed designer surfactants to allow several classes of transformations (e.g., Suzuki-Miyaura, Olefin Metathesis, 1,4-Addition to Enones) to be performed in water. Three generations – PTS, TPGS-750-M (neat and aqueous solution), and Nok – are available in our catalog and encapsulate the reactive species within a micelle, allowing for efficient reactivity at room temperature.
Prof. Lipshutz is also known for work with organocopper reagents. Some have been commercialized, including the "cuprate in a bottle" (324175) and "CuH in a bottle" (762458). His group has contributed several reagents that are used routinely in the community, such as the SEM protecting group precursor SEM-Cl (238902) and Mitsunobu coupling reagent DCAD (680850) as a recoverable alternative to DEAD.
Lipshutz Group Website
Research. Development. Production.
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