Sulfonyl fluorides are privileged protein-reactive functional groups due to their context-specific reactivity with a broad range of amino acid residues (tyrosine, serine, lysine, threonine, cysteine, and histidine). As a result, they are ideally suited to a myriad of applications in chemical biology and drug discovery. To highlight the growing utility of sulfonyl fluoride chemical probes, examples will be provided from the literature and work in which Dr. Jones has been involved.
What Will You Learn?
Topics to be discussed include
Dr. Lyn Jones
Head of Rare Diseases Chemistry, Chemical Biology
Chemistry and synthesis
Session 1:presented January 1, 2016
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