MilliporeSigma

CACNA1H

calcium channel, voltage-dependent, T type, alpha 1H subunit

Synonyms:
CACNA1HB, Cav3.2, ECA6, EIG6
Species:
UniProtKB ID:
Gene ID:
  • Human(8912) Summary: This gene encodes a T-type member of the alpha-1 subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell. There are multiple isoforms of each of the proteins in the complex, either encoded by different genes or the result of alternative splicing of transcripts. Alternate transcriptional splice variants, encoding different isoforms, have been characterized for the gene described here. Studies suggest certain mutations in this gene lead to childhood absence epilepsy (CAE). [provided by RefSeq, Jul 2008]
  • Mouse(58226) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • Rat(114862) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • dog(403533) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • domestic cat(101090071) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • domestic guinea pig(100720102) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • naked mole-rat(101712631) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • chicken(416526) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • cow(282412) calcium channel, voltage-dependent, T type, alpha 1H subunit

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Small Molecule - Allosteric Modulator

Product Number
Description
Species
Gabapentin solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Gabapentin, European Pharmacopoeia (EP) Reference Standard,
Species
human
Gabapentin, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Gabapentin, United States Pharmacopeia (USP) Reference Standard,
Species
human
Pregabalin, European Pharmacopoeia (EP) Reference Standard,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Calcium Channel CaV3.2 (α1H) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Species Reactivity
rat
Application
western blot
Anti-Cav3.2 Antibody, Chemicon®, from rabbit,
Species Reactivity
rat
Application
western blot
Anti-CACNA1H antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Anti-CACNA1H antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-Cav3.2 Calcium Channel Subunit Antibody, clone N55/10, clone N55/10, from mouse,
Species Reactivity
human, mouse
Application
western blot

Small Molecule - Blocker

Product Number
Description
Species
Ethosuximide, European Pharmacopoeia (EP) Reference Standard,
Species
human
Ethosuximide, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Ethosuximide, United States Pharmacopeia (USP) Reference Standard,
Species
human
Ethosuximide, British Pharmacopoeia (BP) Reference Standard,
Species
human
Trimethadione, European Pharmacopoeia (EP) Reference Standard,
Species
human

Proteins

Product Number
Description
Species
PrEST Antigen CACNA1H, Prestige Antigens Powered by Atlas Antibodies, buffered aqueous solution,
Species
human