MilliporeSigma

DDX50

DEAD (Asp-Glu-Ala-Asp) box polypeptide 50

Synonyms:
GU2, GUB, RH-II/GuB, mcdrh
Species:
UniProtKB ID:
Gene ID:
  • Human(79009) Summary: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box enzyme that may be involved in ribosomal RNA synthesis or processing. This gene and DDX21, also called RH-II/GuA, have similar genomic structures and are in tandem orientation on chromosome 10, suggesting that the two genes arose by gene duplication in evolution. This gene has pseudogenes on chromosomes 2, 3 and 4. Alternative splicing of this gene generates multiple transcript variants, but the full length nature of all the other variants but one has not been defined. [provided by RefSeq, Jul 2008]
  • Mouse(94213) DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
  • Rat(361848) DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
  • Domestic Rabbit(100346393) DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
  • cow(534331) DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
  • Horse(100063192) DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
  • sheep(101106650) DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
  • chicken(768898) DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
  • domestic guinea pig(100722648) DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
  • domestic cat(101092053) DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
  • dog(612801) DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
  • naked mole-rat(101704536) DEAD (Asp-Glu-Ala-Asp) box polypeptide 50

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-DDX50 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-DDX50 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-DDX50 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-DDX50 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Ddx50,
Species
mouse
MISSION® esiRNA, targeting human DDX50,
Species
human