MilliporeSigma

GABRA1

gamma-aminobutyric acid (GABA) A receptor, alpha 1

Synonyms:
ECA4, EJM, EJM5
Species:
UniProtKB ID:
Gene ID:
  • Human(2554) Summary: This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(14394) gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
  • Rat(29705) gamma-aminobutyric acid (GABA) A receptor, alpha 1
  • domestic guinea pig(100721626) gamma-aminobutyric acid (GABA) A receptor, alpha 1
  • cow(780973) gamma-aminobutyric acid (GABA) A receptor, alpha 1
  • dog(489143) gamma-aminobutyric acid (GABA) A receptor, alpha 1
  • naked mole-rat(101719179) gamma-aminobutyric acid (GABA) A receptor, alpha 1
  • Zebrafish(768183) gamma-aminobutyric acid (GABA) A receptor, alpha 1
  • sheep(101117759) gamma-aminobutyric acid (GABA) A receptor, alpha 1
  • chicken(374214) gamma-aminobutyric acid (GABA) A receptor, alpha 1
  • domestic cat(100286792) gamma-aminobutyric acid (GABA) A receptor, alpha 1

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Small Molecule - Agonist

Product Number
Description
Species
Piperidine-4-sulfonic acid, ,
Species
human
Isoguvacine hydrochloride, solid,
Species
human
Muscimol hydrobromide, ≥98% (HPLC), solid,
Species
human
Gaboxadol hydrochloride, solid, ≥98% (HPLC),
Species
human
Meprobamate, United States Pharmacopeia (USP) Reference Standard,
Species
human

Small Molecule - Allosteric Modulator

Product Number
Description
Species
Zaleplon solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Zolpidem for system suitability, CRS, European Pharmacopoeia (EP) Reference Standard,
Species
human
Zaleplon, United States Pharmacopeia (USP) Reference Standard,
Species
human
Zolpidem solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
5α-Pregnan-3α-ol-11,20-dione, powder, ≥98% (TLC),
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
Norfloxacin, analytical standard, ≥98% (TLC),
Species
rat, human
Ciprofloxacin, ≥98% (HPLC),
Species
rat, human
Ofloxacin, fluoroquinolone antibiotic,
Species
rat, human
Etiocholan-3α-ol-17-one, ,
Species
human, rat
Ro 15-4513, solid,
Species
rat, human

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-GABRA1 antibody produced in mouse, clone S96-55, 1 mg/mL, purified immunoglobulin,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
western blot
Anti-GABA Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
all, rat
Application
ELISA
immunohistochemistry
Anti-GABA Antibody, serum, Chemicon®,
Species Reactivity
all, rat
Application
ELISA
immunohistochemistry
Anti-GABA Rabbit pAb, lyophilized, Calbiochem®,
Species Reactivity
rat
Application
Anti-GABA Antibody, clone 5A9, clone 5A9, Chemicon®, from mouse,
Species Reactivity
mammals
Application
ELISA
immunohistochemistry

western blot

Small Molecule - Inhibitor

Product Number
Description
Species
2,6-Dimethylphenol, ≥99.5%,
Species
human
Amentoflavone, ≥98.0% (HPLC),
Species
human
2,6-Dimethylphenol, 99%,
Species
human
1,3-Diisopropylbenzene, 96%,
Species
human
2-Isopropylphenol, 98%,
Species
human

Small Molecule - Ligand

Product Number
Description
Species
Ethyl alcohol, Pure, 200 proof, for molecular biology,
Species
human
Etomidate, >98% (HPLC), powder,
Species
human
Flumazenil, >99% (HPLC), solid,
Species
rat, human
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
Species
human
Carbamazepine, powder,
Species
rat, human

Small Molecule - Mixed Agonist/Antagonist

Product Number
Description
Species
2-Cyclopentylphenol, technical grade, 95%,
Species
human
Phenol solution, certified reference material, 500 μg/mL in methanol,
Species
human
2-tert-Butyl-6-methyl-phenol, 99%,
Species
human
2,6-Dimethylbenzenethiol, ≥95%, FG,
Species
human
2,6-Dimethylbenzenethiol, 95%,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Gabra1,
Species
mouse
MISSION® esiRNA, targeting human GABRA1,
Species
human