MilliporeSigma

IL12A

interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)

Synonyms:
CLMF, IL-12A, NFSK, NKSF1, P35
Species:
UniProtKB ID:
Gene ID:
  • Human(3592) Summary: This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity. [provided by RefSeq, Jul 2008]
  • Mouse(16159) interleukin 12a
  • Rat(84405) interleukin 12A
  • domestic guinea pig(100379543) interleukin 12a
  • chicken(407090) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • Zebrafish(445410) interleukin 12a
  • Horse(100034215) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • domestic cat(493741) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • dog(403977) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • cow(281856) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • Goat(100861293) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • sheep(443064) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • naked mole-rat(101701392) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)

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ELISA

Product Number
Description
Species
Human IL-12 p70 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human
Rhesus Macaque IL12A / IL12B ELISA Kit, ,
Species
Porcine IL12A / IL12B ELISA Kit, ,
Species
Mouse IL-12 P40/70 ELISA Kit, for serum, plasma and cell culture supernatant,
Species
mouse

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Interleukin-12 antibody produced in goat, IgG fraction of antiserum,
Species Reactivity
mouse
Application
neutralization
western blot
Anti-Interleukin-12 antibody produced in goat, IgG fraction of antiserum, lyophilized powder,
Species Reactivity
human
Application
neutralization
Anti-IL-12 alpha Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human
Application
immunohistochemistry
western blot

Proteins

Product Number
Description
Species
IL-12 from mouse, recombinant, expressed in CHO cells, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
mouse
IL-12 human, recombinant, expressed in CHO cells, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
human
Interleukin-12 from mouse, ≥97% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture,
Species
mouse
Interleukin-12 human, ≥97% (SDS-PAGE and N-terminal analysis), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture,
Species
human
IL-35 (mouse): FC (human), recombinant, expressed in CHO cells,
Species
mouse

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Il12a,
Species
mouse
MISSION® esiRNA, targeting human IL12A,
Species
human