MilliporeSigma

LRP1

low density lipoprotein receptor-related protein 1

Synonyms:
A2MR, APOER, APR, CD91, IGFBP3R, LRP, LRP1A, TGFBR5
Species:
UniProtKB ID:
Gene ID:
  • Human(4035) Summary: The protein encoded by this gene is an endocytic receptor involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the A2M-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer patients. [provided by RefSeq, Jan 2010]
  • Mouse(16971) low density lipoprotein receptor-related protein 1
  • Rat(299858) low density lipoprotein receptor-related protein 1
  • dog(481124) low density lipoprotein receptor-related protein 1
  • cow(533894) low density lipoprotein receptor-related protein 1
  • sheep(101120656) low density lipoprotein receptor-related protein 1
  • chicken(396170) low density lipoprotein receptor-related protein 1
  • domestic guinea pig(100726418) low density lipoprotein receptor-related protein 1
  • Domestic Rabbit(100009571) low density lipoprotein receptor-related protein 1
  • Thale Cress(831108) lateral root primordium protein-like protein
  • fruit fly(35799) LDL receptor protein 1
  • naked mole-rat(101723541) low density lipoprotein receptor-related protein 1
  • domestic cat(101090780) low density lipoprotein receptor-related protein 1
  • Domestic Rabbit(100009547) low density lipoprotein receptor-related protein 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-LRP1 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-LRP1 Antibody, Intracellular domain, serum, from rabbit,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-LRP1 85kDa subunit Antibody, clone 4G7, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse, rat
Application
flow cytometry
immunocytochemistry

western blot
Anti-LRP-1 Antibody, clone 11H4, clone 11H4, from mouse,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-LRP, Light Chain Mouse mAb (5A6), liquid, clone 5A6, Calbiochem®,
Species Reactivity
human, mouse, rabbit
Application

Proteins

Product Number
Description
Species
PrEST Antigen LRP1, Prestige Antigens Powered by Atlas Antibodies, buffered aqueous solution,
Species
human
PrEST Antigen LRP1, Prestige Antigens Powered by Atlas Antibodies, buffered aqueous solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human LRP1,
Species
human