MilliporeSigma

PADI2

peptidyl arginine deiminase, type II

Synonyms:
PAD-H19, PAD2, PDI2
Species:
UniProtKB ID:
Gene ID:
  • Human(11240) Summary: This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq, Jul 2008]
  • Mouse(18600) peptidyl arginine deiminase, type II
  • Rat(29511) peptidyl arginine deiminase, type II
  • dog(487414) peptidyl arginine deiminase, type II
  • chicken(428172) peptidyl arginine deiminase, type II
  • Zebrafish(386792) peptidyl arginine deiminase, type II
  • naked mole-rat(101721485) peptidyl arginine deiminase, type II
  • domestic cat(101085301) peptidyl arginine deiminase, type II
  • Horse(100050025) peptidyl arginine deiminase, type II
  • sheep(101108464) peptidyl arginine deiminase, type II
  • domestic guinea pig(100728531) peptidyl arginine deiminase, type II
  • cow(617851) peptidyl arginine deiminase, type II

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PADI2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, horse, human
Application
western blot
Anti-PADI2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

Proteins

Product Number
Description
Species
PAD2, GST tagged from mouse, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
mouse
PADI-2 human, recombinant, expressed in baculovirus infected Sf9 cells, ≥60% (SDS-PAGE),
Species
human
PrEST Antigen PADI2, Prestige Antigens Powered by Atlas Antibodies, buffered aqueous solution,
Species
human
PAD Cocktail, Active, recombinant,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Padi2,
Species
mouse
MISSION® esiRNA, targeting human PADI2,
Species
human