MilliporeSigma

PCGF2

polycomb group ring finger 2

Synonyms:
MEL-18, RNF110, ZNF144
Species:
UniProtKB ID:
Gene ID:
  • Human(7703) Summary: The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryogenesis, cell cycles, and tumorigenesis. This protein was shown to act as a negative regulator of transcription and has tumor suppressor activity. The expression of this gene was detected in various tumor cells, but is limited in neural organs in normal tissues. Knockout studies in mice suggested that this protein may negatively regulate the expression of different cytokines, chemokines, and chemokine receptors, and thus plays an important role in lymphocyte differentiation and migration, as well as in immune responses. [provided by RefSeq, Jul 2008]
  • Mouse(22658) polycomb group ring finger 2
  • Rat(287662) polycomb group ring finger 2
  • sheep(101120343) polycomb group ring finger 2
  • domestic cat(101087022) polycomb group ring finger 2
  • chicken(425919) polycomb group ring finger 2
  • naked mole-rat(101721189) polycomb group ring finger 2
  • dog(491035) polycomb group ring finger 2
  • Horse(100055282) polycomb group ring finger 2
  • cow(505147) polycomb group ring finger 2
  • domestic guinea pig(100719492) polycomb group ring finger 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-PCGF2 antibody produced in mouse, clone 4D6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Monoclonal Anti-PCGF2 antibody produced in mouse, clone 4C10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, rat
Application
ELISA
western blot
Anti-PCGF2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-PCGF2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-MEL18/PCGF2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Pcgf2,
Species
mouse
MISSION® esiRNA, targeting human PCGF2,
Species
human
MISSION® esiRNA, targeting human PCGF2 (2),
Species
human