MilliporeSigma

PLAGL1

pleiomorphic adenoma gene-like 1

Synonyms:
LOT1, ZAC, ZAC1
Species:
UniProtKB ID:
Gene ID:
  • Human(5325) Summary: This gene encodes a C2H2 zinc finger protein with transactivation and DNA-binding activities. It has been shown to have anti-proliferative properties, and thus thought to function as a tumor suppressor. In addition, overexpression of this gene during fetal development is believed to underlie the rare disorder, transient neonatal diabetes mellitus (TNDM). This gene is imprinted, with preferential expression of the paternal allele in many tissues, however, biallelic expression has been noted in peripheral blood leucocytes. A recent study reports that tissue-specific imprinting results from variable utilization of monoallelic and biallelic promoters. Many transcript variants differing in the 5' UTR and encoding two different isoforms, have been found for this gene. [provided by RefSeq, Oct 2010]
  • Mouse(22634) pleiomorphic adenoma gene-like 1
  • Rat(25157) pleiomorphic adenoma gene-like 1
  • sheep(101119399) pleiomorphic adenoma gene-like 1
  • cow(539761) pleiomorphic adenoma gene-like 1
  • domestic guinea pig(100735816) pleiomorphic adenoma gene-like 1
  • naked mole-rat(101718544) pleiomorphic adenoma gene-like 1
  • chicken(421664) pleiomorphic adenoma gene-like 1
  • dog(484018) pleiomorphic adenoma gene-like 1
  • domestic cat(101092436) pleiomorphic adenoma gene-like 1

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PLAGL1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
western blot
Monoclonal Anti-PLAGL1 antibody produced in mouse, clone 1E2, ascites fluid,
Species Reactivity
human
Application
ELISA
western blot
Anti-PLAGL1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence

Proteins

Product Number
Description
Species
PrEST Antigen PLAGL1, Prestige Antigens Powered by Atlas Antibodies, buffered aqueous solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PLAGL1,
Species
human