MilliporeSigma

PTP4A1

protein tyrosine phosphatase type IVA, member 1

Synonyms:
HH72, PRL-1, PRL1, PTP(CAAX1), PTPCAAX1
Species:
UniProtKB ID:
Gene ID:
  • Human(7803) Summary: This gene encodes a member of a small class of prenylated protein tyrosine phosphatases (PTPs), which contain a PTP domain and a characteristic C-terminal prenylation motif. The encoded protein is a cell signaling molecule that plays regulatory roles in a variety of cellular processes, including cell proliferation and migration. The protein may also be involved in cancer development and metastasis. This tyrosine phosphatase is a nuclear protein, but may associate with plasma membrane by means of its prenylation motif. Pseudogenes related to this gene are located on chromosomes 1, 2, 5, 7, 11 and X. [provided by RefSeq, Jun 2013]
  • Mouse(19243) protein tyrosine phosphatase 4a1
  • Rat(29463) protein tyrosine phosphatase type IVA, member 1
  • domestic guinea pig(100730701) protein tyrosine phosphatase type IVA, member 1
  • naked mole-rat(101724177) protein tyrosine phosphatase type IVA, member 1
  • dog(481863) protein tyrosine phosphatase type IVA, member 1
  • cow(613326) protein tyrosine phosphatase type IVA, member 1
  • chicken(421877) protein tyrosine phosphatase type IVA, member 1
  • Zebrafish(493615) protein tyrosine phosphatase type IVA, member 1

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Antibodies

Product Number
Description
Species Reactivity
Application
ANTI-PRL1 antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human, mouse
Application
western blot
Anti-PTP4A1 (C-terminal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
canine, human, mouse, rat
Application
ELISA
western blot
Anti-PTP4A1/PRL-1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot

Proteins

Product Number
Description
Species
PRL-1 (2-173) Active human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PTP4A1,
Species
human
MISSION® esiRNA, targeting mouse Ptp4a1,
Species
mouse