MilliporeSigma

ROCK2

Rho-associated, coiled-coil containing protein kinase 2

Synonyms:
ROCK-II
Species:
UniProtKB ID:
Gene ID:
  • Human(9475) Summary: The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho. [provided by RefSeq, Jul 2008]
  • Mouse(19878) Rho-associated coiled-coil containing protein kinase 2
  • Rat(25537) Rho-associated coiled-coil containing protein kinase 2
  • domestic cat(101094501) Rho-associated, coiled-coil containing protein kinase 2
  • sheep(101103800) Rho-associated, coiled-coil containing protein kinase 2
  • chicken(374182) Rho-associated, coiled-coil containing protein kinase 2
  • naked mole-rat(101724195) Rho-associated, coiled-coil containing protein kinase 2
  • cow(282041) Rho-associated, coiled-coil containing protein kinase 2
  • sheep(100294663) Rho-associated, coiled-coil containing protein kinase 2
  • domestic guinea pig(100713798) Rho-associated, coiled-coil containing protein kinase 2
  • dog(482970) Rho-associated, coiled-coil containing protein kinase 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-phospho-ROCK2 (pTyr722) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
western blot
Monoclonal Anti-ROCK2 antibody produced in mouse, clone 2A4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot
Anti-ROCK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-ROCK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Monoclonal Anti-ROCK2, (C-terminal) antibody produced in mouse, clone 1E12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

immunohistochemistry

western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Y-27632 dihydrochloride, ≥98% (HPLC),
Species
human
Adenine, ≥99%,
Species
human, rat, mouse
Adenine, BioReagent, suitable for cell culture,
Species
human, rat, mouse
Adenine, BioReagent, suitable for plant cell culture, ≥99%,
Species
human, rat, mouse

Proteins

Product Number
Description
Species
ROCK2 (5-554), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ROCK2,
Species
human