MilliporeSigma

TIMP1

TIMP metallopeptidase inhibitor 1

Synonyms:
CLGI, EPA, EPO, HCI, TIMP
Species:
UniProtKB ID:
Gene ID:
  • Human(7076) Summary: This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq, Jul 2008]
  • Mouse(21857) tissue inhibitor of metalloproteinase 1
  • Rat(116510) TIMP metallopeptidase inhibitor 1
  • domestic cat(101095886) TIMP metallopeptidase inhibitor 1
  • naked mole-rat(101722238) TIMP metallopeptidase inhibitor 1
  • dog(403816) TIMP metallopeptidase inhibitor 1
  • cow(282092) TIMP metallopeptidase inhibitor 1
  • domestic guinea pig(101787552) TIMP metallopeptidase inhibitor 1
  • sheep(443331) TIMP metallopeptidase inhibitor 1
  • Horse(100034220) TIMP metallopeptidase inhibitor 1

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ELISA

Product Number
Description
Species
Feline TIMP1 / Tissue Inhibitor of Metalloproteinase-1 ELISA Kit, ,
Species
domestic cat
Rhesus Macaque TIMP-1 ELISA, for serum, plasma and cell culture supernatants,
Species
Porcine TIMP1 / Metalloproteinase Inhibitor 1 ELISA Kit, ,
Species
Rat TIMP-1 ELISA Kit, for cell and tissue lysates,
Species
rat
Human TIMP-1 ELISA Kit, for cell and tissue lysates,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-TIMP-1 Antibody, Chemicon®, from rabbit,
Species Reactivity
bovine, ferret, horse, rabbit, rat, sheep
Application
ELISA
immunohistochemistry

western blot
Anti-TIMP1 Antibody, clone 5O7P1, Rabbit Monoclonal, ,
Species Reactivity
human
Application
western blot
Anti-TIMP-1 Antibody, clone 7-6C1, clone 7-6C1, Chemicon®, from mouse,
Species Reactivity
bovine, human, rat
Application
ELISA
immunohistochemistry

western blot
Anti-TIMP1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-TIMP1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot

Proteins

Product Number
Description
Species
PrEST Antigen TIMP1, Prestige Antigens Powered by Atlas Antibodies, buffered aqueous solution,
Species
human
TIMP1 human, recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE),
Species
human
TIMP-1 human, recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture,
Species
human
TIMP-1, recombinant, active human, ,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Timp1,
Species
mouse
MISSION® esiRNA, targeting human TIMP1,
Species
human