MilliporeSigma

TNNI2

troponin I type 2 (skeletal, fast)

Synonyms:
AMCD2B, DA2B, FSSV, fsTnI
Species:
UniProtKB ID:
Gene ID:
  • Human(7136) Summary: This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009]
  • Mouse(21953) troponin I, skeletal, fast 2
  • Rat(29389) troponin I type 2 (skeletal, fast)
  • chicken(396386) troponin I type 2 (skeletal, fast)
  • cow(790768) troponin I, fast skeletal muscle-like
  • cow(506434) troponin I type 2 (skeletal, fast)
  • sheep(101121135) troponin I type 2 (skeletal, fast)
  • Domestic Rabbit(100009581) troponin I type 2 (skeletal, fast)
  • dog(475995) troponin I type 2 (skeletal, fast)
  • naked mole-rat(101717320) troponin I type 2 (skeletal, fast)
  • domestic guinea pig(100722531) troponin I type 2 (skeletal, fast)

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ELISA

Product Number
Description
Species
Human Troponin I ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Troponin I2 (TNNI2) Antibody, clone 2H7S10, Rabbit Monoclonal, ,
Species Reactivity
mouse, rat
Application
immunofluorescence
western blot
Anti-TNNI2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-TNNI2 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
western blot
Anti-TNNI2 antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
bovine, dog, goat, guinea pig, horse, human, rabbit, rat
Application
western blot
Anti-TNNI2 Rabbit pAb, liquid, Calbiochem®,
Species Reactivity
human, mouse
Application

Proteins

Product Number
Description
Species
PrEST Antigen TNNI2, Prestige Antigens Powered by Atlas Antibodies, buffered aqueous solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human TNNI2,
Species
human
MISSION® esiRNA, targeting mouse Tnni2,
Species
mouse